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Words to know: Anemia and iron deficiency

Anemia
Too few healthy red blood cells or too little hemoglobin, which can cause tiredness and shortness of breath.
Hemoglobin
The protein in red blood cells that carries oxygen.
Red blood cells
Blood cells that carry oxygen from the lungs to the rest of the body.
Iron
A mineral the body needs to make hemoglobin. It comes from food or supplements.
Iron deficiency
Not having enough iron stored in the body.
Ferritin
A protein that stores iron. Its blood level shows how much iron your body has saved.
Transferrin saturation (TSAT)
The percent of the iron-carrying protein in your blood that is filled with iron.
TIBC
Total iron binding capacity. A test of how much room the blood has to carry iron.
MCV
Mean corpuscular volume. The average size of your red blood cells.
Reticulocyte
A young red blood cell, just released from the bone marrow.
Bone marrow
The soft tissue inside bones where blood cells are made.
Vitamin B12
A vitamin needed for red blood cells and healthy nerves. It comes from animal foods.
Folate
A B vitamin, also called folic acid, needed to make red blood cells.
Anemia of chronic disease
Anemia caused by long-term inflammation, which makes the body hold back iron. Also called anemia of inflammation.
Erythropoietin (EPO)
A hormone made by the kidneys that tells the bone marrow to make red blood cells.
IV iron
Iron given directly into a vein through a small tube.
Colonoscopy
A test that uses a thin tube with a camera to look inside the large bowel.
Upper endoscopy
A test that uses a thin tube with a camera to look at the food pipe, stomach, and upper small bowel.
Celiac disease
A condition where eating gluten damages the small bowel and blocks absorption of iron and other nutrients.
Blood transfusion
Getting donated blood or red blood cells through a vein.
Hypophosphatemia
A low level of phosphate in the blood, which can happen after some IV iron products.
Pica
Craving and eating things that are not food, like ice or clay. It can be a sign of low iron.
Hematologist
A doctor who specializes in blood conditions.

Last updated: 2026-10-27. Medically reviewed by Veli Bakalov, MD, medical oncologist (October 2026). General education from Step by Step, the patient portal of HemeOncBuddy.