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Words to know: Blood clots (DVT and PE)

Blood clot (thrombus)
A clump of blood that has turned from liquid into a gel.
Deep vein thrombosis (DVT)
A clot in a deep vein, usually in the leg.
Pulmonary embolism (PE)
A clot that has traveled to the blood vessels in the lungs.
Venous thromboembolism (VTE)
A term that covers both DVT and PE.
Vein
A blood vessel that carries blood back to the heart.
Anticoagulant (blood thinner)
A medicine that keeps clots from growing and stops new clots from forming.
DOAC
Direct oral anticoagulant. A newer blood thinner pill such as apixaban or rivaroxaban.
Low molecular weight heparin (LMWH)
A blood thinner given as a shot under the skin, such as enoxaparin.
Warfarin
An older blood thinner pill that needs regular INR blood tests.
INR
A blood test that shows how well warfarin is working.
D-dimer
A blood test that measures a piece of a broken-down clot.
Ultrasound
A painless test that uses sound waves to make pictures of the inside of the body.
CT pulmonary angiogram
A CT scan with dye that shows the blood vessels in the lungs.
Provoked clot
A clot with a clear short-term trigger, such as surgery or injury.
Unprovoked clot
A clot with no clear trigger.
Thrombophilia
A condition, inherited or acquired, that makes the blood clot more easily.
Factor V Leiden
A common inherited gene change that raises the risk of clots.
Antiphospholipid syndrome (APS)
An immune condition where antibodies make blood more likely to clot.
Thrombolysis
Clot-busting treatment that dissolves a clot quickly but raises bleeding risk.
IVC filter
A small device placed in a large belly vein to catch clots before they reach the lungs.
Post-thrombotic syndrome
Long-term leg swelling, pain, or skin changes after a DVT.
HIT (heparin-induced thrombocytopenia)
A rare immune reaction to heparin that lowers platelets and causes clots.
Platelets
Small blood cells that help blood clot and stop bleeding.

Last updated: 2026-10-27. Medically reviewed by Veli Bakalov, MD, medical oncologist (October 2026). General education from Step by Step, the patient portal of HemeOncBuddy.