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Words to know: Breast cancer

Aromatase inhibitor
A hormone therapy pill that lowers estrogen in women past menopause.
Antibody-drug conjugate
A targeted antibody attached to a chemotherapy medicine that delivers it to cancer cells.
Biopsy
Removing a small piece of tissue to check it for cancer.
BRCA1 and BRCA2
Genes that, when changed, raise the risk of breast, ovarian, and other cancers.
DCIS
Ductal carcinoma in situ. Abnormal cells that stay inside the milk ducts.
Estrogen
A female hormone that can help some breast cancers grow.
HER2
A protein on some cancer cells that helps them grow.
Hormone receptor
A protein on cells that attaches to estrogen or progesterone.
Immunotherapy
Treatment that helps your immune system find and attack cancer.
Invasive cancer
Cancer that has grown out of where it started into nearby tissue.
Lumpectomy
Surgery that removes the tumor and some normal tissue, but keeps most of the breast.
Lymph nodes
Small bean-shaped organs that fight infection. Cancer can spread to them.
Lymphedema
Swelling, often in the arm, after lymph nodes are removed or treated.
Mastectomy
Surgery to remove the whole breast.
Metastatic
Cancer that has spread to other parts of the body.
Neoadjuvant therapy
Treatment given before surgery, often to shrink the tumor.
Adjuvant therapy
Treatment given after surgery to lower the chance of cancer coming back.
Pathologic complete response
No invasive cancer is found at surgery after treatment given before surgery.
Palliative care
Care that eases symptoms and improves quality of life at any stage.
Recurrence
Cancer that comes back after treatment.
Sentinel lymph node
The first lymph node or nodes where cancer is likely to spread.
Targeted therapy
Medicine that attacks a specific protein or gene change in cancer cells.
Triple-negative
Breast cancer without estrogen receptors, progesterone receptors, or extra HER2.

Last updated: 2026-10-27. Medically reviewed by Veli Bakalov, MD, medical oncologist (October 2026). General education from Step by Step, the patient portal of HemeOncBuddy.