Step by Stepa HemeOncBuddy patient portal

Words to know: Thyroid cancer

Anaplastic
Cells that look very different from normal cells and grow very fast.
Biopsy
Removing cells or tissue to check for cancer under a microscope.
Calcitonin
A hormone made by C cells. It is a tumor marker for medullary thyroid cancer.
Differentiated
Cancer cells that still look and act a lot like normal cells.
Endocrinologist
A doctor who treats hormone and gland problems, including the thyroid.
Fine needle aspiration (FNA)
A biopsy that uses a thin needle to take cells from a lump.
Levothyroxine
A pill that replaces the hormone your thyroid normally makes.
Lobectomy
Surgery to remove one half (lobe) of the thyroid.
Lymph nodes
Small bean-shaped glands that are part of the immune system. Cancer can spread to them.
MEN2
An inherited syndrome caused by a RET gene change. It raises the risk of medullary thyroid cancer and some other gland tumors.
Metastatic
Cancer that has spread from where it started to other parts of the body.
Nodule
A lump. Most thyroid nodules are not cancer.
Parathyroid glands
Four tiny glands next to the thyroid that control calcium levels in the blood.
Radioactive iodine (RAI)
A treatment that uses radioactive iodine to destroy thyroid cells and some thyroid cancer cells.
RAI-refractory
Thyroid cancer that no longer responds to radioactive iodine.
Recurrence
When cancer comes back after treatment.
Stage
A way to describe how big the cancer is and how far it has spread.
Targeted therapy
Medicine that blocks a specific gene change or protein in cancer cells.
Thyroglobulin
A protein made by thyroid cells. After treatment, it is used as a tumor marker.
Thyroidectomy
Surgery to remove the thyroid gland.
TSH
Thyroid stimulating hormone. It tells the thyroid to grow and make hormone.
TSH suppression
Taking enough thyroid hormone to keep TSH low, which may slow cancer growth.
Ultrasound
A scan that uses sound waves to make pictures.
Clinical trial
A research study that tests new treatments in people.

Last updated: 2026-10-27. Medically reviewed by Veli Bakalov, MD, medical oncologist (October 2026). General education from Step by Step, the patient portal of HemeOncBuddy.