Mirvetuximab soravtansine

Say it: mir-veh-TUX-ih-mab sor-av-TAN-seen · Brand names: Elahere
Mirvetuximab soravtansine is a targeted medicine that delivers a strong cancer drug straight to cancer cells that have a protein called folate receptor alpha.
What it is
It is made of two parts joined together: an antibody that finds a protein called folate receptor alpha on cancer cells, and a strong cancer medicine. The antibody carries the medicine straight to the cancer cell, so more of it reaches the cancer and less reaches healthy cells. A test on your tumor shows if you can get this medicine.
Often used for
- ovarian cancer
- fallopian tube cancer
- primary peritoneal cancer (cancer of the lining of the belly)
How you get it
You get it as an infusion into a vein at a clinic. It is usually given once every 3 weeks, and you get medicines before each infusion to help prevent reactions and nausea. Your schedule may be different.
Common side effects and what helps
- Blurry vision or other vision changes. Use your eye drops as directed and do not drive if you cannot see clearly.
- Dry eyes or eye discomfort. Use lubricating eye drops as your team tells you.
- Feeling tired. Rest and short walks can help.
- Nausea. Eat small, bland meals.
- Belly pain. Tell your team if it is new or gets worse.
- Diarrhea or constipation. Drink fluids and tell your team if it lasts.
- Numbness or tingling in your hands or feet. Tell your team if it gets worse.
Call your care team right away if you have
- Any new or worse vision problems, eye pain, or sensitivity to light
- New or worse cough, shortness of breath, or chest pain
- A fever of 100.4 degrees Fahrenheit (38 degrees Celsius) or higher
- Very bad belly pain, swelling, or vomiting
- Trouble breathing, chills, flushing, or rash during or after the infusion
Before you start, tell your team
- If you have eye or vision problems or wear contact lenses
- If you already have numbness or tingling
- If you are pregnant, may become pregnant, or are breastfeeding
- All the medicines, vitamins, and herbal products you take
Good to know
- This medicine can cause serious eye problems. You will have eye exams before you start and during treatment.
- Your team will ask you to use steroid eye drops and lubricating eye drops on a set schedule. Do not wear contact lenses unless your eye doctor says it is okay.
- This medicine can cause pneumonitis (swelling in the lungs). Tell your team about new breathing problems.
- This medicine can harm an unborn baby. Ask your team about birth control during treatment and for months after.
At home
- Use your steroid and lubricating eye drops exactly on the schedule your team gives you.
- Do not wear contact lenses during treatment unless your eye doctor says it is okay.
- Do not drive or use machines if your vision is blurry.
Questions to ask
- How do I use my eye drops, and for how long?
- How often will I see the eye doctor?
- Was my tumor tested for folate receptor alpha?
- What should I do if my vision changes?
Side effect guides
Sources
Quick answers
- What is Mirvetuximab soravtansine?
- Mirvetuximab soravtansine is a targeted medicine that delivers a strong cancer drug straight to cancer cells that have a protein called folate receptor alpha. Brand names: Elahere.
- What is Mirvetuximab soravtansine used for?
- ovarian cancer; fallopian tube cancer; primary peritoneal cancer (cancer of the lining of the belly).
- How is Mirvetuximab soravtansine given?
- You get it as an infusion into a vein at a clinic. It is usually given once every 3 weeks, and you get medicines before each infusion to help prevent reactions and nausea. Your schedule may be different.
- What are the common side effects of Mirvetuximab soravtansine?
- Blurry vision or other vision changes. Dry eyes or eye discomfort. Feeling tired. Nausea. Belly pain. Diarrhea or constipation. Numbness or tingling in your hands or feet.
- When should I call my care team while taking Mirvetuximab soravtansine?
- Any new or worse vision problems, eye pain, or sensitivity to light; New or worse cough, shortness of breath, or chest pain; A fever of 100.4 degrees Fahrenheit (38 degrees Celsius) or higher; Very bad belly pain, swelling, or vomiting; Trouble breathing, chills, flushing, or rash during or after the infusion.
Last updated: 2026-10-27. Medically reviewed by Veli Bakalov, MD, medical oncologist (October 2026). General education from Step by Step, the patient portal of HemeOncBuddy.